Beyond glucose: bypass the bottleneck
A new way to recover from hypos — combining fast carbs with adaptive energy for complete recovery
A new approach
Klario is designed to bypass the brain’s energy bottleneck using adaptive energy with fast carbs
Built and proven by experts
Developed by leading diabetes specialists and studied across 1000+ real-world hypos
Achieving complete recovery
In studies: Klario delivered 27% fewer recurrent hypos and got 75% back to their day faster
CGM tested in real world hypos
Klario has been studied in a randomized clinical study of more than 1,000 self‑treated hypos in adults with type 1 diabetes
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fewer repeat lows in the 2 hours after treating a hypo
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fewer days in glucose highs and lows over a year
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Analysis showed:
- Fewer repeat lows after a hypo, with more time in range in the 2 hours following treatment
- Less time spent in glucose extremes, adding up to 10 days in total over 1 year
Proven to get your day back faster
Real-world improvements in how people feel and function after a hypo with Klario
“I usually have a crash pattern where you go up and down all day — I haven’t had that with Klario.”
Julia, clinical trial participant
"The fatigue and brain fog definitely improved. It made a huge difference at work; I could actually go about my day instead of being written off."
Thomas, clinical trial participant
How Klario feels in everyday life
Beyond numbers on a graph, people in the study told us Klario helped them feel and function better after a hypo
The problem: an energy bottleneck
During a hypo, your brain runs low on its usual fuel—glucose. Even after levels return to normal, it may struggle to use that glucose efficiently, creating an ‘energy bottleneck’ that can leave you feeling wiped out and foggy.
How Klario works
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Corrects glucose
Klario contains 15g of fast‑acting carbohydrate to raise blood sugar, just like standard treatments
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Adds adaptive energy
It also provides adaptive energy that the brain can use through different pathways when glucose use is limited
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Supports clearer recovery
Bypassing the energy bottleneck, Klario fuels the brain directly, helping reduce brain fog and the “hypo hangover”
What is adaptive energy?
Your body’s built-in backup fuel system—activated when glucose runs low, helping keep your brain and body functioning.
BHB is one example. Produced by the liver, it rises during fasting, or intense exercise—and provides an additional energy source when glucose alone isn’t enough.
Led by experts in diabetes care
The Klario clinical program was led by Prof. Russell‑Jones, leading clinician with extensive experience in type 1 diabetes research
Klario offers a new way to support recovery – not just correcting the CGM number, but helping people feel and function better afterwards.
Join future Klario Research
We’re continuing to explore how Klario can better support people living with diabetes through future research. Register your interest below and we’ll contact you when a relevant study opens.
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The Hidden Impact of Hypos
Register for the surveyRegister for our upcoming survey on the real-world impact of hypos, including recovery, the hypo hangover, and challenges during exercise
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Klario & Sport
Register interest“Tell me when there are studies on using Klario around exercise and sport.”
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Klario & Sleep
Register interest“Tell me when there are studies on using Klario during night‑time hypos.”
See the evidence for yourself
Discover why 100% of our clinical trial participants said they would recommend Klario to others
Clinically proven. Mechanism-driven.
Klario is built on rigorous clinical research, combining fast-acting carbohydrates with adaptive energy to support more complete recovery after hypoglycaemia.
Our studies explore objective CGM data, real-world outcomes and underlying metabolic mechanisms — helping explain not just that Klario works, but why.